Theodorus van der Kwast Selected Research

Type 3 Fibroblast Growth Factor Receptor (Fibroblast Growth Factor Receptor 3)

6/2014	Fibroblast growth factor receptor 3 activation plays a causative role in urothelial cancer pathogenesis in cooperation with Pten loss in mice.
2/2008	Strong immunohistochemical expression of fibroblast growth factor receptor 3, superficial staining pattern of cytokeratin 20, and low proliferative activity define those papillary urothelial neoplasms of low malignant potential that do not recur.

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Theodorus van der Kwast Research Topics

Disease

44	Prostatic Neoplasms (Prostate Cancer) 01/2022 - 01/2009
39	Neoplasms (Cancer) 01/2022 - 02/2008
7	Neoplasm Metastasis (Metastasis) 01/2022 - 01/2017
4	Noninfiltrating Intraductal Carcinoma (DCIS) 01/2022 - 01/2019
4	Genomic Instability 11/2021 - 12/2014
3	Urinary Bladder Neoplasms (Bladder Cancer) 04/2022 - 06/2014
3	Adenocarcinoma 01/2022 - 08/2012
2	Carcinoma (Carcinomatosis) 08/2020 - 10/2019
2	Hypoxia (Hypoxemia) 01/2019 - 12/2014
2	Disease Progression 01/2017 - 11/2010
1	Lymphatic Metastasis 01/2022
1	Urinary Incontinence 01/2022
1	Prostatic Intraepithelial Neoplasia 11/2021
1	Contracture 01/2020
1	Adenomatous Polyposis Coli (Familial Adenomatous Polyposis) 07/2017
1	Carcinogenesis 01/2016
1	Renal Cell Carcinoma (Grawitz Tumor) 12/2011
1	Polyps 12/2011
1	Wilms Tumor (Wilm's Tumor) 11/2010
1	Graft vs Host Disease (Graft-Versus-Host Disease) 09/2008

Drug/Important Bio-Agent (IBA)

21	Biomarkers (Surrogate Marker)IBA 01/2022 - 01/2009
11	DNA (Deoxyribonucleic Acid)IBA 01/2022 - 01/2009
9	Prostate-Specific Antigen (Semenogelase)IBA 12/2020 - 03/2009
6	NucleotidesIBA 11/2021 - 07/2015
5	AndrogensIBA 01/2019 - 07/2009
4	Transcription Factors (Transcription Factor)IBA 01/2020 - 09/2017
3	RNA (Ribonucleic Acid)IBA 10/2021 - 01/2019
3	Hormones (Hormone)IBA 01/2020 - 01/2016
3	ChromatinIBA 10/2019 - 07/2013
2	Androgen Receptors (Androgen Receptor)IBA 01/2020 - 10/2017
2	Proteins (Proteins, Gene)FDA Link 10/2019 - 06/2013
2	Type 3 Fibroblast Growth Factor Receptor (Fibroblast Growth Factor Receptor 3)IBA 06/2014 - 02/2008
2	EnzymesIBA 04/2014 - 06/2013
1	Indicators and Reagents (Reagents)IBA 01/2022
1	Messenger RNA (mRNA)IBA 10/2021
1	Fibroblast Growth Factor Receptors (Fibroblast Growth Factor Receptor)IBA 08/2020
1	NectinsIBA 08/2020
1	B7-H1 AntigenIBA 08/2020
1	Oxygen (Dioxygen)IBA 01/2019
1	MicroRNAs (MicroRNA)IBA 01/2019
1	Circular RNAIBA 01/2019
1	ProteomeIBA 01/2019
1	Long Noncoding RNAIBA 01/2018
1	Prostaglandins AIBA 01/2018
1	cytidylyl-(3'-5')-cytidine (CpC)IBA 01/2018
1	GP 4 (GP4)IBA 07/2017
1	Kallikreins (Kallikrein)IBA 01/2017
1	N 563IBA 01/2017
1	Formaldehyde (Formol)FDA Link 10/2016
1	ParaffinIBA 10/2016
1	Biological ProductsIBA 01/2016
1	Intergenic DNA (Junk DNA)IBA 01/2016
1	SteroidsIBA 01/2016
1	Complement System Proteins (Complement)IBA 12/2014
1	Protein-Tyrosine Kinases (Tyrosine Kinase)IBA 06/2014
1	1,2- di- (4- sulfamidophenyl)- 4- butylpyrazolidine- 3,5- dione (DSB)IBA 09/2013
1	ML 7IBA 09/2013
1	Protease NexinsIBA 11/2012
1	Protein SIBA 10/2012
1	Retinoic Acid 4-Hydroxylase (CYP26B1)IBA 05/2012
1	1,1'- (4,4,7,7- tetramethyl- 4,7- diazaundecamethylene)bis- 4- (3- methyl- 2,3- dihydro(benzo- 1,3- thiazole)- 2- methylidene)quinolinium (TOTO)IBA 12/2011
1	VimentinIBA 12/2011
1	Keratins (Keratin)IBA 12/2011
1	Platelet-Derived Growth FactorIBA 11/2010
1	platelet-derived growth factor AIBA 11/2010
1	Minor Histocompatibility AntigensIBA 09/2008
1	HLA Antigens (Human Leukocyte Antigens)IBA 09/2008
1	Interferon-gamma (Interferon, gamma)IBA 09/2008
1	HA-1 antigenIBA 09/2008
1	Keratin-20 (Cytokeratin 20)IBA 02/2008

Therapy/Procedure

12	Prostatectomy (Retropubic Prostatectomy) 01/2022 - 04/2014
12	Therapeutics 01/2022 - 10/2012
7	Radiotherapy 01/2022 - 09/2013
6	Castration 10/2021 - 10/2012
2	Image-Guided Radiotherapy 01/2019 - 12/2014
1	Cystectomy 04/2022
1	Cystotomy 01/2020
1	Contraindications 01/2020
1	Nephroureterectomy 10/2019
1	Neoadjuvant Therapy 01/2019
1	Precision Medicine 02/2015
1	Extracorporeal Shockwave Therapy 08/2012
1	Nephrectomy 12/2011
1	Stem Cell Transplantation 09/2008